BDBM50179183 CHEMBL576840::NSC-3198
SMILES OC(=O)C(CSSCC(NC(=O)Cc1ccccc1)C(O)=O)NC(=O)Cc1ccccc1
InChI Key InChIKey=DWRCRIMPBCLETK-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50179183
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of amyloid beta (1 to 40) (unknown origin) aggregationMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair