BDBM50179641 1-(3-chlorophenyl)-3-(1-methylpyrrolidin-2-ylidene)urea::CHEMBL380626

SMILES CN1CCCC1=NC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=SINSISHOQIDCEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179641   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179641(1-(3-chlorophenyl)-3-(1-methylpyrrolidin-2-ylidene...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179641(1-(3-chlorophenyl)-3-(1-methylpyrrolidin-2-ylidene...)
Affinity DataIC50:  620nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed