BDBM50181501 CHEMBL3818589

SMILES CCN([C@@H]1CN(N=C1c1ccc(Cl)c(Cl)c1)C(\Nc1cccc(OC(F)F)c1)=N/C#N)C(=O)CO

InChI Key InChIKey=OTTJIRVZJJGFTK-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181501   

TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181501(CHEMBL3818589)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181501(CHEMBL3818589)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed