BDBM50187436 1-(6-Bromopyridin-3-yl)-piperazine::1-(6-bromopyridin-3-yl)piperazine::CHEMBL209824

SMILES Brc1ccc(cn1)N1CCNCC1

InChI Key InChIKey=OVRZSDRDBJDKBF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187436   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187436(1-(6-Bromopyridin-3-yl)-piperazine | 1-(6-bromopyr...)
Affinity DataIC50:  182nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50187436(1-(6-Bromopyridin-3-yl)-piperazine | 1-(6-bromopyr...)
Affinity DataIC50:  180nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187436(1-(6-Bromopyridin-3-yl)-piperazine | 1-(6-bromopyr...)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed