BDBM50202106 CHEMBL218758::E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-N-(5-hydroxy-adamantan-2-yl)-propionamide

SMILES C[C@H](N1CC[C@@H](F)C1)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key InChIKey=ZFNDDTOHDPHZON-IXXSQMGDSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202106   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202106(CHEMBL218758 | E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-...)
Affinity DataKi:  21nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202106(CHEMBL218758 | E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-...)
Affinity DataKi:  24nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202106(CHEMBL218758 | E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202106(CHEMBL218758 | E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against mouse 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202106(CHEMBL218758 | E-(2S)-(3R-fluoro-pyrrolidin-1-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed