BDBM50207094 CHEMBL3976282::US9550741, I-2
SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1
InChI Key InChIKey=AHJHJVULSVKBEA-WGSAOQKQSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50207094
Affinity DataKi: 0.0560nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor expressed in CHO cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 0.0560nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 0.0560nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 0.150nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]ketanserin from recombinant human 5-HT2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 0.150nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]spiperone from recombinant human D2L receptor expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.10nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.10nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair