BDBM50216505 1,5-di-[4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxy]-3-oxapentane::CHEMBL392146

SMILES CC1=NC(=S)NC(C1C(=O)OCCOCCOC(=O)C1C(NC(=S)N=C1C)c1cccc(O)c1)c1cccc(O)c1

InChI Key InChIKey=IALQRJCHCBIIQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216505   

TargetKinesin-like protein KIF11(Human)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50216505(1,5-di-[4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Eg5 ATPase activity expressed in Escherichia coli after 12 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50216505(1,5-di-[4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of microtubule-stimulated Eg5 ATPase activity expressed in Escherichia coli after 12 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed