BDBM50236613 CHEMBL4069898
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)N[C@@H]2CCC[C@]2(C)C(=O)NO)c2ccccc2n1
InChI Key InChIKey=XCMYDYMUMRJGDR-VWNXMTODSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50236613
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of TACE in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulati...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair