BDBM50239658 CHEMBL4100679

SMILES CC(C)C1(c2c(C)[nH]nc2OC(N)=C1C#N)c1cc(cc(c1)C(F)(F)F)-c1cccc(CCC(O)=O)c1

InChI Key InChIKey=ULXPNGMLUPLOIA-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239658   

TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239658(CHEMBL4100679)
Affinity DataIC50:  165nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed