BDBM50240416 CHEMBL23838::O,O-diethyl O-p-nitrophenyl phosphate::diethyl 4-nitrophenyl phosphate::diethyl p-nitrophenyl phosphate::diethyl paraoxon::ethyl paraoxon::p-nitrophenyl diethyl phosphate::paraoxon::phosphacol::phosphoric acid diethyl 4-nitrophenyl ester

SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=WYMSBXTXOHUIGT-UHFFFAOYSA-N

Data  2 KI  11 IC50  1 Kd  3 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50240416   

TargetMuscarinic acetylcholine receptor DM1(Drosophila melanogaster)
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]QNB from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor DM1(Drosophila melanogaster)
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  5.90E+3nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  13nMAssay Description:Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  338nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  59nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of esterase activity of mouse carbonic anhydrase 13 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKoff:  567s-1Assay Description:Inhibition of rat brain AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKoff:  267s-1Assay Description:Inhibition of rat brain AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataKoff:  333s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  540nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed