BDBM50240416 CHEMBL23838::O,O-diethyl O-p-nitrophenyl phosphate::diethyl 4-nitrophenyl phosphate::diethyl p-nitrophenyl phosphate::diethyl paraoxon::ethyl paraoxon::p-nitrophenyl diethyl phosphate::paraoxon::phosphacol::phosphoric acid diethyl 4-nitrophenyl ester
SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O
InChI Key InChIKey=WYMSBXTXOHUIGT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50240416
TargetMuscarinic acetylcholine receptor DM1(Drosophila melanogaster)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]QNB from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor DM1(Drosophila melanogaster)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 338nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of esterase activity of mouse carbonic anhydrase 13 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Missouri St. Louis
Curated by ChEMBL
University Of Missouri St. Louis
Curated by ChEMBL
Affinity DataKd: 1.70E+5nMAssay Description:Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKoff: 567s-1Assay Description:Inhibition of rat brain AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
Affinity DataKoff: 267s-1Assay Description:Inhibition of rat brain AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Missouri St. Louis
Curated by ChEMBL
University Of Missouri St. Louis
Curated by ChEMBL
Affinity DataKoff: 333s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair