BDBM50240683 2-Phenyl-isothiazol-3-one::2-phenylisothiazol-3(2H)-one::CHEMBL99594::cid_11052198

SMILES O=c1ccsn1-c1ccccc1

InChI Key InChIKey=VFUQPOSQUAVDEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240683   

TargetGlucose-6-phosphate 1-dehydrogenase(Leuconostoc mesenteroides)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50: >2.50E+4nMAssay Description:Excerpt from MH082340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African sleep...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50:  1.35E+4nMAssay Description:Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African slee...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay