BDBM50243050 (S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(4-(trifluoromethyl)phenyl)thiophen-2-yl)urea::CHEMBL469686

SMILES NC(=O)Nc1sc(cc1C(=O)N[C@H]1CCCNC1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UDSXVNXEFKMNPJ-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243050   

TargetCyclin-dependent kinase 2-associated protein 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243050((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(4-(trifluoro...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243050((S)-1-(3-(piperidin-3-ylcarbamoyl)-5-(4-(trifluoro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed