BDBM50247490 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid::CHEMBL448246::cid_651854

SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O

InChI Key InChIKey=RRXQHLQCQYPPMF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50247490   

TargetCollagenase 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  4.82E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant MMP9 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant MMP8 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant MMP13 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247490(4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed