BDBM50249579 CHEMBL1477694::US10729695, Compound CB-3

SMILES Cc1nc2ccccc2n1CC(O)Cn1c2ccccc2c2ccccc12

InChI Key InChIKey=JPPYNSLIOBRLRO-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249579   

TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50249579(CHEMBL1477694 | US10729695, Compound CB-3)
Affinity DataKd:  18nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50249579(CHEMBL1477694 | US10729695, Compound CB-3)
Affinity DataKd:  1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed