BDBM50251023 CHEMBL458568::N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide

SMILES Oc1c(F)cc(NS(=O)(=O)c2ccccc2)cc1F

InChI Key InChIKey=YAWFBTGILXVPSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251023   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(CHEMBL458568 | N-(3,5-Difluoro-4-hydroxyphenyl)ben...)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of aldose reductase in rat lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(CHEMBL458568 | N-(3,5-Difluoro-4-hydroxyphenyl)ben...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(CHEMBL458568 | N-(3,5-Difluoro-4-hydroxyphenyl)ben...)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of Fischer-344 rat lens ALR2 by least-square analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed