BDBM50258085 4-(4-(benzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic acid::CHEMBL492768

SMILES OC(=O)C(=O)CC(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=KMRYXNIEUDTYAJ-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258085   

TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50258085(4-(4-(benzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataKi:  1.99E+3nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50258085(4-(4-(benzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataEC50:  6.80E+3nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50258085(4-(4-(benzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataIC50:  3.99E+4nMAssay Description:Inhibition of SCV helicase assessed as duplex-DNA unwinding by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50258085(4-(4-(benzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of ATPase activity of SCV helicase assessed as phosphate release by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed