BDBM50259647 CHEMBL4100727

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)NCc1ccc(F)c(F)c1)B(O)O

InChI Key InChIKey=NOUFGJXBMSVSAG-PMACEKPBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259647   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259647(CHEMBL4100727)
Affinity DataIC50:  2nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259647(CHEMBL4100727)
Affinity DataIC50:  110nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259647(CHEMBL4100727)
Affinity DataIC50:  340nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed