BDBM50260279 (R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(phenyl)methanone::CHEMBL522806::[(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE

SMILES CN1C(=S)N[C@@H](C(C(=O)c2ccccc2)=C1C)c1cccc(O)c1

InChI Key InChIKey=JGBBILLMZPWNFU-QGZVFWFLSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260279   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of basal ATPase activity of human Eg5More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair