BDBM50268994 (5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4-methoxypiperidin-1-yl)methanone::CHEMBL522236

SMILES COC1CCN(CC1)C(=O)c1cc2cc(OC3CCN(CC3)C(C)C)ccc2[nH]1

InChI Key InChIKey=WKMRKBPUKMGAQZ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268994   

TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268994BDBM50268994((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...)
Affinity DataEC50:  9nMAssay Description:Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268994BDBM50268994((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268994BDBM50268994((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed