BDBM50272526 CHEMBL497293::Icariside II

SMILES [#6]-[#8]-c1ccc(cc1)-c1oc2c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc(-[#8])c2c(=O)c1-[#8]-[#6@@H]-1-[#8]-[#6@H](-[#6])-[#6@@H](-[#8])-[#6@H](-[#8])-[#6@@H]-1-[#8]

InChI Key InChIKey=NGMYNFJANBHLKA-XAPMVYOVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272526   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of Milan

Curated by ChEMBL
LigandPNGBDBM50272526(CHEMBL497293 | Icariside II)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed