BDBM50277639 CHEMBL484609::N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylthio)phenyl)propionamide
SMILES CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)cc(n2)N2CCN(C)CC2)cc1
InChI Key InChIKey=LCQYMDMUCJFFKN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50277639
Affinity DataKi: 1.60nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 603nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair