BDBM50287328 CHEMBL38513::[3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-prop-(E)-ylideneaminooxy]-acetic acid
SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccccn3)cc12
InChI Key InChIKey=AGNDBGHZXDFOKQ-XICOUIIWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50287328
TargetArachidonate 5-lipoxygenase-activating protein/Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassayMore data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein/Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair