BDBM50289012 2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one::2-(2-Fluorophenyl)-4H-3,1-benzoxazin-4-one (1)::CHEMBL161656

SMILES Fc1ccccc1-c1nc2ccccc2c(=O)o1

InChI Key InChIKey=UHJQEWLULUOONU-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289012   

TargetChymotrypsinogen A(Bos taurus (bovine))
University Of Karachi

LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataKi:  4.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetComplement C1r subcomponent(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataIC50: >6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen A(Bos taurus (bovine))
University Of Karachi

LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataIC50:  6.50E+3nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataIC50: >6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article