BDBM50291791 6,6-Dimethyl-1-[3-(naphthalen-1-yloxymethyl)-phenyl]-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL20466

SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(COc2cccc3ccccc23)c1

InChI Key InChIKey=JHWDJVFPABOYEB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50291791   

TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291791(6,6-Dimethyl-1-[3-(naphthalen-1-yloxymethyl)-pheny...)
Affinity DataKi:  5.37nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50291791(6,6-Dimethyl-1-[3-(naphthalen-1-yloxymethyl)-pheny...)
Affinity DataKi:  39.8nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50291791(6,6-Dimethyl-1-[3-(naphthalen-1-yloxymethyl)-pheny...)
Affinity DataKi:  71nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291791(6,6-Dimethyl-1-[3-(naphthalen-1-yloxymethyl)-pheny...)
Affinity DataKi:  135nMAssay Description:Inhibition of human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed