BDBM50299031 2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-yl)thiazolo[4,5-b]pyridine::CHEMBL573034

SMILES COc1cc(ccn1)-c1cnc2nc(sc2c1)N1CCC(CC1)N1CCCCC1

InChI Key InChIKey=CQCYZYXYLGEQJN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299031   

TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299031(2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-y...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299031(2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-y...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50299031(2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-y...)
Affinity DataIC50:  204nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed