BDBM50299061 CHEMBL573935::[2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid

SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HGICQEUHJFERNR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299061   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  260nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  290nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Affinity DataIC50:  510nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed