BDBM50303420 6-(3,5-Difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile::6-[(3,5-difluorophenyl)amino]-9-ethyl-9H-purine-2-carbonitrile::CHEMBL567341
SMILES CCn1cnc2c(Nc3cc(F)cc(F)c3)nc(nc12)C#N
InChI Key InChIKey=SZYYBVWPURUFRR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50303420
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human Kallikrein 4More data for this Ligand-Target Pair
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of human Proteinase KMore data for this Ligand-Target Pair
Affinity DataIC50: 44.7nMAssay Description:Inhibition of papaya papainMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 34.7nMAssay Description:Inhibition of human Cathepsin CMore data for this Ligand-Target Pair
Affinity DataIC50: 933nMAssay Description:Inhibition of human Cathepsin X/ZMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.24E+4nMAssay Description:Inhibition of human MMP14More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of human TACEMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of human Caspase 4More data for this Ligand-Target Pair