BDBM50304410 CHEMBL594108::cis-2-[(E)-4-(1H-Imidazol-1-yl)but-2-enyl]-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
SMILES COc1ccc(cc1OC)C1=NN(C\C=C\Cn2ccnc2)C(=O)[C@@H]2CC=CC[C@H]12
InChI Key InChIKey=IGHBBDMZIFZXDF-OBNUAKFSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50304410
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550
Curated by ChEMBL
Kyoto 601-8550
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair