BDBM50307884 3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BIPHENYL-4-YL SULFAMATE::5'-((1H-1,2,4-Triazol-1-yl)methyl)-3-chloro-2'-cyanobiphenyl-4-yl Sulfamate::CHEMBL592131

SMILES NS(=O)(=O)Oc1ccc(cc1Cl)-c1cc(Cn2cncn2)ccc1C#N

InChI Key InChIKey=ZUTFDMVDCHXOFA-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50307884   

TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  86nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin)More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human CA2 by colorimetric assayMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed