BDBM50319836 4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1H-indole-7-carboxamido)cyclopropyl)benzoic acid::CHEMBL1086490
SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12
InChI Key InChIKey=IFKQAJFRAOXFQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50319836
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 561nMAssay Description:Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...More data for this Ligand-Target Pair