BDBM50320721 4-Amino-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol::4-amino-3-(pyridin-4-yl)-1H-1,2,4-triazole-5(4H)-thione::CHEMBL571510

SMILES Nn1c(n[nH]c1=S)-c1ccncc1

InChI Key InChIKey=LHSIJUVRXSETDR-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320721   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50320721(4-Amino-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol ...)
Affinity DataKi:  1.01E+3nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50320721(4-Amino-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol ...)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50320721(4-Amino-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol ...)
Affinity DataIC50:  4.43E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using p-nitrophenyl phosphate as substrate preincubated for 10 mins before substrate addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50320721(4-Amino-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol ...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed