BDBM50336822 4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,2R)-2-phenylcyclopropyl]piperidine-1-carboxamide::CHEMBL1615216::rac-4-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-N-(trans-2-phenylcyclopropyl)piperidine-1-carboxamide

SMILES CC(C)c1noc(n1)C1CCN(CC1)C(=O)N[C@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=WYQYSMZPAAVISB-SJORKVTESA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336822   

TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50336822(4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50336822(4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50336822(4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,...)
Affinity DataIC50:  13nMAssay Description:Inhibition of soluble epoxide hydrolase in human HepG2 cells after 30 minsMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50336822(4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,...)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat soluble epoxide hydrolase in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50336822(4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human soluble epoxide hydrolase in cell free systemMore data for this Ligand-Target Pair