BDBM50337288 3-[N-(4-methylphenyl)amino]benzoic acid::CHEMBL1682207::US9271961, 12

SMILES Cc1ccc(Nc2cccc(c2)C(O)=O)cc1

InChI Key InChIKey=PFABVCLRTFWWEY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337288   

TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 700nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 700nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 5.60E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed