BDBM50341383 CHEMBL4175607

SMILES Cc1[nH]c2c(N3CCO[C@H](CO)C3)c(C#N)c(nc2c1Cl)C(F)(F)F

InChI Key InChIKey=ATFQBBCQZKVZJN-QMMMGPOBSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50341383   

TargetSodium-dependent phosphate transport protein 2A(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataKi:  750nMAssay Description:Displacement of (C[3H]3) from NaPi2a (unknown origin) expressed in HEK293 cell membranes coexpressing tetracyclin after 1 hr by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2C(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of rat NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2C(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2A(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2A(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50:  540nMAssay Description:Inhibition of mouse NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human NaPi2b expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transporter 1(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human Pit-1 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transport protein 2A(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50:  380nMAssay Description:Inhibition of human NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent phosphate transporter 2(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50341383(CHEMBL4175607)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human Pit-2 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed