BDBM50342728 CHEMBL1771260::N1-(3-(2,6-dichloro-4-ethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl)-N2-(tetrahydro-2H-pyran-4-yl)ethane-1,2-diamine

SMILES CCOc1cc(Cl)c(-c2c(C)nn3c(NCCNC4CCOCC4)cc(C)nc23)c(Cl)c1

InChI Key InChIKey=KXVKWNPVAHBIOP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342728   

TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342728(CHEMBL1771260 | N1-(3-(2,6-dichloro-4-ethoxyphenyl...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342728(CHEMBL1771260 | N1-(3-(2,6-dichloro-4-ethoxyphenyl...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at NPY Y1 receptor in human SK-N-MC cells assessed as inhibition of NPY-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed