BDBM50367033 COENZYME_A

SMILES CC(C)(CO[P@@](O)(=O)O[P@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS

InChI Key InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-N

Data  1 KI  3 IC50  1 Kd

PDB links: 725 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50367033   

TargetCholine O-acetyltransferase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of choline acetyltransferase isolated from squid head gangliaMore data for this Ligand-Target Pair
TargetN-alpha-acetyltransferase 50(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataKd:  156nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in by SPR analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50:  4.19E+4nMAssay Description:Inhibition of PCAF HAT domain (493-658) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50:  8.23E+4nMAssay Description:Inhibition of recombinant Tip60 (1-513) expressed in Escherichia coli BL21 (DE3) by liquid scintillationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50:  4.59E+4nMAssay Description:Inhibition of recombinant p300More data for this Ligand-Target Pair