BDBM50370518 CHEMBL4176474::US10954217, Example 00229
SMILES O=C(OCc1ccccc1)N1Cc2ccc(cc2C1)N1CCN(CC1)C1CCCC1
InChI Key InChIKey=FUWNTUBEOVLTGS-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50370518
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataKi: 165nMAssay Description:Displacement of [3H]-alpha-methylhistamine from human histamine H3 receptor expressed in HEK Flp-In cells after 90 mins by microbeta scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 594nMAssay Description:Displacement of [3H]-Pyrilamine from human histamine H1 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 1.07E+3nMAssay Description:Displacement of [125I]-iodoaminopotentidine from human histamine H2 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation c...More data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Displacement of [3H]-Rauwolscine from human adrenergic alpha2C receptor expressed in stable MDCK cells after 90 mins by microbeta scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 2.14E+3nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair