BDBM50393510 CHEMBL1232082

SMILES [O-][N+](=O)c1cccc(c1)-n1c2ncccc2c(=O)n(Cc2ccncc2)c1=O

InChI Key InChIKey=YLHRMVRLIOIWTO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393510   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50393510(CHEMBL1232082)
Affinity DataIC50:  22nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50393510(CHEMBL1232082)
Affinity DataEC50:  17nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed