BDBM50422384 CHEMBL216443

SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1cccc(CNCCCCCCNCCSSCCNCCCCCCNCc2cccc(c2)C(=O)N2CCN(CC2)c2nc(N)c3cc(OC)c(OC)cc3n2)c1

InChI Key InChIKey=LWYWVWVBCDLOEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422384   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50422384(CHEMBL216443)
Affinity DataIC50:  3.89E+3nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1A-adrenoreceptors on isolated prostatic Vas deferens from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50422384(CHEMBL216443)
Affinity DataIC50:  5.50E+4nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1B-adrenoreceptors on isolated spleen from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50422384(CHEMBL216443)
Affinity DataIC50:  81nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed