BDBM50429754 CHEMBL1981977::N-(2-Chlorophenyl)Cinnamamide

SMILES Clc1ccccc1NC(=O)\C=C\c1ccccc1

InChI Key InChIKey=FKLXMLNUDVRAJG-ZHACJKMWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429754   

Target72 kDa type IV collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429754(CHEMBL1981977 | N-(2-Chlorophenyl)Cinnamamide)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50429754(CHEMBL1981977 | N-(2-Chlorophenyl)Cinnamamide)
Affinity DataIC50:  9.86E+3nMAssay Description:Inhibition of autophosphorylation of His6-tagged EGFR cytoplasmic domain (unknown origin) expressed in Sf9 cells by DELFIA time resolved fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429754(CHEMBL1981977 | N-(2-Chlorophenyl)Cinnamamide)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429754(CHEMBL1981977 | N-(2-Chlorophenyl)Cinnamamide)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed