BDBM50438671 CHEMBL2414537

SMILES COc1ccc(cc1)-c1cccn2nc(Nc3cnn(c3)C3CCOCC3)nc12

InChI Key InChIKey=MNHPVHGSTQRKND-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438671   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438671(CHEMBL2414537)
Affinity DataKi:  0.700nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438671(CHEMBL2414537)
Affinity DataIC50:  87nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as reduction of phosphorylated STAT5 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed