BDBM50446304 CHEMBL3109337

SMILES COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@@H]3CCNC[C@H]3F)c2n1

InChI Key InChIKey=PPPOUAQYRUUFNJ-WIYYLYMNSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50446304   

TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  70nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  767nMAssay Description:Inhibition of cFMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  767nMAssay Description:Inhibition of cFMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  70nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed