BDBM50447292 CHEMBL3113979
SMILES C[C@H]1COCCN1C[C@H]1CN(CCN1c1ccc(cc1)[C@@](C)(O)C(F)(F)F)S(=O)(=O)c1cccs1
InChI Key InChIKey=OJTJLEFGCNYTBQ-RBDMOPTHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50447292
Affinity DataEC50: 1.79E+3nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human glucokinaseMore data for this Ligand-Target Pair
Affinity DataEC50: 82nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair