BDBM50454321 CHEMBL4208135

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]C([#6])([#8])[#6]-1-[#6]-c2c(-[#8]-1)c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1c2oc2ccc(-[#8])cc2c1=O

InChI Key InChIKey=DKJQBBIHCDRRLL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50454321   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50454321(CHEMBL4208135)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50454321(CHEMBL4208135)
Affinity DataKi:  9.90E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50454321(CHEMBL4208135)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50454321(CHEMBL4208135)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed