BDBM50491728 CHEMBL2385557::US10865384, Compound IM-4
SMILES Cc1cccc(c1)-c1nc([nH]c1-c1ccncc1)-c1ccc2ccccc2c1F
InChI Key InChIKey=FSSVIZLKIGCSBI-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50491728
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences
Curated by ChEMBL
Institute Of Chemical And Engineering Sciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant GST-tagged p38alpha MAP kinase (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences
Curated by ChEMBL
Institute Of Chemical And Engineering Sciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology And Research
US Patent
Agency For Science, Technology And Research
US Patent
Affinity DataIC50: 277nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology And Research
US Patent
Agency For Science, Technology And Research
US Patent
Affinity DataIC50: 277nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology And Research
US Patent
Agency For Science, Technology And Research
US Patent
Affinity DataIC50: 490nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology And Research
US Patent
Agency For Science, Technology And Research
US Patent
Affinity DataIC50: 490nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair