BDBM50502488 CHEMBL4449942::US11834430, Compound 62
SMILES N#Cc1ccc(OCCOc2cccc(c2)-n2ccnc2C2CC2)cc1
InChI Key InChIKey=AZJIYOCNWUEQAE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50502488
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair