BDBM50521251 CHEMBL4443236
SMILES [H][C@@]12CN(CCN1c1nc(nc3cc(c(Cl)c(OC2)c13)-c1c(C)ccc2[nH]ncc12)N1CC(C1)N(C)C)C(=O)C=C
InChI Key InChIKey=FKHASWQIAUADON-SFHVURJKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50521251
Affinity DataIC50: 21nMAssay Description:Inhibition of GDP loaded biotin-labeled KRAS G12C mutant (unknown origin) assessed as reduction in guanine nucleotide exchange preincubated for 4 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of GDP loaded biotin-labeled KRAS G12C mutant (unknown origin) assessed as reduction in guanine nucleotide exchange preincubated for 4 hrs...More data for this Ligand-Target Pair