BDBM50526893 CHEMBL4586954
SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSCc2ccccc2CSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(F)cc2)C(=O)NNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)CNC1=O
InChI Key InChIKey=PYJOZFZUINVNAW-FTMHIQFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50526893
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]-diprenorphine from human DOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-diprenorphine from human MOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 293nMAssay Description:Displacement of [3H]-diprenorphine from human KOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
Affinity DataEC50: 142nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
Affinity DataEC50: 806nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human DOR expressed in CHO cell membranes assessed as reduction in SNC80-induced response incubated for 1 hr by [35S]-GTPgamma...More data for this Ligand-Target Pair