BDBM50534270 CHEMBL4464463

SMILES CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(CNc2ccc(cc2)S(=O)(=O)Nc2nc(C)cc(C)n2)CC1

InChI Key InChIKey=RUBMSPWXSHZTRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534270   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50534270(CHEMBL4464463)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed