BDBM50538511 CHEMBL4642409

SMILES COc1ccc(cc1OC)-c1cnn2c(N)c(-c3ccccc3)c(OCCCN(C)C)nc12

InChI Key InChIKey=ATYKMHIJRBRZOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538511   

TargetTranscription factor ETV6/Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538511(CHEMBL4642409)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of TEL/KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538511(CHEMBL4642409)
Affinity DataIC50:  70nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed